Excedrin® is an over the counter medication that is primarily used as a pain reliever and fever reducer. Its main active ingredients are acetaminophen, caffeine, and aspirin. The maximum amount of the drug that is generally considered safe to consume is 1000 mg at a time and no more than 4000 mg in one day. Although the medication does not require a prescription, an Excedrin® overdose can still be potentially fatal. Show
The signs of an Excedrin® overdose will typically occur in stages. At the start of the overdose, a person may begin to notice a change in appetite, as well as nausea and vomiting. He or she may also experience sharp pains in the lower abdominal, and may become fatigued or disorientated. As the drug makes its way through the bloodstream, a person may start to also feel severe pain in the upper abdominal. During the later stages of an Excedrin® overdose, a person may notice having darker colored urine than normal and the nails and whites of the eyes may have a yellowed hue. Other overdose symptoms may include ringing in the ears. This ringing of the ears may be accompanied by diarrhea or a headache. Although at the start of an Excedrin® overdose, a person may feel fatigued or disorientated, as it goes on, these symptoms may be replaced with feelings of agitation or lightheadedness, and even hallucinations in some cases. A sudden change in heartbeat and convulsions may also occur during an overdose. In some cases, it may take a smaller amount of the medication to be considered an overdose. For people with sensitivities to acetaminophen, bleeding of the stomach and intestines can occur if even a small amount of Excedrin® is taken. If stomach and intestinal bleeding occurs, it will usually cause symptoms like black, tarry, or bloody stool or vomit, coughing up blood, and fainting. Stomach and intestinal bleeding can be potentially life-threatening and immediate medical attention should be sought if these symptoms occur. A negative reaction to the acetaminophen in Excedrin® can also result in serious damage to the liver. Liver damage can cause nausea, fever, abdominal pain, and appetite suppression. Other signs of liver damage are yellowing of the eyes or skin, a condition known as jaundice, as well as discoloration or the urine and stool. Immediate medical attention is also recommended in the instance of liver damage symptoms. What to know about the symptoms you might be experiencing—and how to handle them.When you have headache pain, there’s a good chance you want relief from the pain—fast. Over-the-counter medications like Excedrin® can help ease your distress. While deciding which Excedrin® treatment is right for you, it’s useful to understand the uses, warnings, and side effects of each medication as well as how to handle them should they occur. EXCEDRIN® EXTRA STRENGTHExcedrin® Extra Strength can help you temporarily relieve minor aches and pains due to headache, a cold, arthritis, muscular aches, toothache, premenstrual and menstrual cramps. The warnings and side effects of Excedrin® Extra Strength are: Reye’s syndrome: Children and teenagers who have or are recovering from chicken pox or flu-like symptoms should not use this product. When using this product, if changes in behavior with nausea and vomiting occur, consult a doctor because these symptoms could be an early sign of Reye’s syndrome, a rare but serious illness. Allergy alert: Acetaminophen may cause severe skin reactions. Symptoms may include: • skin reddening If a skin reaction occurs, stop use and seek medical help right away. Allergy alert: Aspirin may cause a severe allergic reaction which may include: • hives Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take • more than 8 caplets in 24 hours, which is the maximum daily amount Stomach bleeding warning: This product contains an NSAID, which may cause severe stomach bleeding. The chance is higher if you • are age 60 or older Caffeine warning: The recommended dose of this product contains about as much caffeine as a cup of coffee. Limit the use of caffeine-containing medications, foods, or beverages while taking this product because too much caffeine may cause nervousness, irritability, sleeplessness, and, occasionally, rapid heart beat. Do not use: • if you have ever had an allergic reaction to acetaminophen, aspirin or any other pain reliever/fever reducer Ask a doctor before use if: • you have liver disease Ask a doctor or pharmacist before use if you are taking: • a prescription drug for diabetes, gout, or arthritis Stop use and ask a doctor if: • an allergic reaction occurs. Seek medical help right away. • feel faint • ringing in the ears or loss of hearing occurs These could be signs of a serious condition. EXCEDRIN® MIGRAINEExcedrin® Migraine treats migraines and is intended for those who have been diagnosed by a doctor. If your migraine is not relieved or worsens after first dose, talk to your doctor. The warnings and side effects of Excedrin® Migraine are: Reye’s syndrome: Children and teenagers who have or are recovering from chicken pox or flu-like symptoms should not use this product. When using this product, if changes in behavior with nausea and vomiting occur, consult a doctor because these symptoms could be an early sign of Reye’s syndrome, a rare but serious illness. Allergy alert: Acetaminophen may cause severe skin reactions. Symptoms may include: •skin reddening If a skin reaction occurs, stop use and seek medical help right away. Allergy alert: Aspirin may cause a severe allergic reaction which may include: • hives Stomach bleeding warning: This product contains an NSAID, which may cause severe stomach bleeding. The chance is higher if you • are age 60 or older Medication overuse headache warning: Headaches may worsen if this product is used for 10 or more days per month. Caffeine warning: The recommended dose of this product contains about as much caffeine as a cup of coffee. Limit the use of caffeine-containing medications, foods, or beverages while taking this product because too much caffeine may cause nervousness, irritability, sleeplessness, and, occasionally, rapid heart beat. Do not use • if you have ever had an allergic
reaction to acetaminophen, aspirin or any other pain reliever/fever reducer Ask a doctor before use if •you have never had migraines diagnosed by a health professional Ask a doctor or pharmacist before use if you are • taking a prescription drug for: Stop use and ask a doctor if • an allergic reaction occurs. Seek medical help right away. • feel faint • your migraine is not relieved or worsens after first dose EXCEDRIN® TENSION HEADACHEExcedrin® Tension Headache temporarily relieves minor aches and pains due to headache and muscle aches. The warnings and side effects of Excedrin® Tension Headache are: Allergy alert: Acetaminophen may cause severe skin reactions. Symptoms may include: • skin reddening If a skin reaction occurs, stop use and seek medical help right away. Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take • more than 6 caplets in 24 hours, which is the maximum daily amount Caffeine warning: The recommended dose of this product contains about as much caffeine as a cup of coffee. Limit the use of caffeine-containing medications, foods, or beverages while taking this product because too much caffeine may cause nervousness, irritability, sleeplessness, and, occasionally, rapid heart beat. Do not use • if you are allergic to acetaminophen Ask a doctor before use if • you have liver disease Ask a doctor or pharmacist before use if you are • taking the blood thinning drug warfarin Stop use and ask a doctor if •any new symptoms occur EXCEDRIN® PM HEADACHEExcedrin® PM Headache is intended for temporary relief of occasional headaches and minor aches and pains with accompanying sleeplessness. The warnings and side effects of Excedrin® PM Headache are: Reye’s syndrome: Children and teenagers who have or are recovering from chicken pox or flu-like symptoms should not use this product. When using this product, if changes in behavior with nausea and vomiting occur, consult a doctor because these symptoms could be an early sign of Reye’s syndrome, a rare but serious illness. Allergy alert: Acetaminophen may cause severe skin reactions. Symptoms may include: • skin reddening Allergy alert: Aspirin may cause a severe allergic reaction which may include: • hives Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take • more than 2 caplets in 24 hours, which is the maximum daily amount Stomach bleeding warning: This product contains an NSAID, which may cause severe stomach bleeding. The chance is higher if you • are age 60 or older Do not use • if you have ever had an allergic reaction
to acetaminophen, aspirin or any other pain reliever/fever reducer Ask a doctor before use if • you have liver disease Ask a doctor or pharmacist before use if you are taking • a prescription drug for: When using this product • drowsiness will occur Stop use and ask a doctor if • an allergic reaction occurs. Seek medical help right
away. • feel faint • sleeplessness persists continuously for more than 2 weeks. Insomnia may be a symptom of a serious underlying medical illness These could be signs of a serious condition. What happens if I take more than 2 Excedrin Migraine in 24 hours?by Drugs.com
Taking more than 2 caplets in 24 hours may cause an overdose of acetaminophen, especially if you are using other medicines that contain acetaminophen. Taking too much acetaminophen may damage your liver or cause death.
What are the side effects of too much Excedrin?Overdose symptoms may include nausea, vomiting, loss of appetite, sweating, stomach/abdominal pain, extreme tiredness, yellowing eyes/skin, and dark urine. Daily alcohol use, especially when combined with acetaminophen, may damage your liver.
Can I take 4 Excedrin Migraine 24 hours?Excedrin Migraine, on the other hand, is FDA approved for migraine relief, and adults 18 years and older are able to take a maximum of 2 tablets in 24 hours.
What happens when you overdose on migraine relief?Symptoms of overdose may include nausea, vomiting, loss of appetite, sweating, burning pain in the throat and stomach, stomach/abdominal pain, extreme tiredness, yellowing eyes/skin, ringing in the ears, rapid/shallow breathing, irregular/fast heartbeat, change in the amount of urine, dark urine, confusion, agitation, ...
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