Post-operative Antibiotic Prophylaxis for Dental and Medical Procedures
Now that you have had a total joint replacement, certain precautions must be taken to reduce the chance of infection developing in the bone or around the implant. These precautions should be followed for 2 years after your joint replacement unless your surgeon tells you that you have a risk factor that makes infection more likely for you (such as immune compromise).
ALL patients who have undergone total joint replacement surgery should receive antibiotic prophylaxis* prior to any dental procedures and additional procedures as outlined below for 2 years after your surgery. After 2 years, you should have prophylaxis* if you have an abnormally weak immune system or are having a root canal or dental extraction (these have a greater risk of infection than a routine cleaning).
- Patients not allergic to penicillin:
Cephalexin or amoxicillin 2 grams orally one hour prior to procedure. - Patients not allergic to penicillin and unable to take oral medications:
Cefazolin 1 gram or ampicillin 2 grams IM/IV one hour prior to the procedure. - Patients allergic to penicillin:
Clindamycin 600 milligrams orally one hour prior to procedure. - Patients allergic to penicillin and unable to take oral medications:
Clindamycin 600 milligrams IM/IV one hour prior to the procedure.
Patients who are having a sigmoidoscopy or colonoscopy:
- Patients not allergic to penicillin:
Cephalexin or amoxicillin 2 grams orally one hour prior to procedure. - Patients allergic to penicillin:
Vancomycin 1 gram intravenously slowly over 1 hour beginning 1 hour before the procedure. PLUS gentamycin 1.5 mg/KG IM or IV 30 minutes before the procedure.
Patients who will have genitourinary manipulation or instrumentation (cystoscopy or TURP, gastrointestinal or biliary surgery, or any gynecological procedures):
Advise your doctor that you have had a prosthesis implanted and that you need to have antibiotic prophylaxis.
Antibiotic prophylaxis is a preventative measure taken to avoid infection.
* If you suspect any infection, you should be seen promptly and treated by your primary care physician.
Antibiotics are not needed for manicures, pedicures, gynecological exams, eye surgery.
Home » Protocols » Antibiotic Prophylaxis Protocol After Total Joint Replacement
Antibiotic Prophylaxis Protocol After Total Joint Replacement
The following precautions should be taken for AT LEAST TWO YEARS after total joint replacement to reduce the risk of infection around the implant. Patients at increased risk of infection should use antibiotic prophylaxis for the rest of their lifetime. These conditions include, and are not limited to:
- Prior history of joint infection
- Weakened immune system (Diabetes, Cancer, Organ Transplant Recipient, Hemophilia)
- Chronic steroid usage
- Malnutrition/poor nutrition
- Inflammatory arthritis
Antibiotic prophylaxis is needed for the following procedures:
- Dental procedures (cleaning, extractions, implants, periodontal work)
- Gastrointestinal procedures (upper endoscopy, colonoscopy)
- Genitourinary procedures (cystoscopy, TURP)
Antibiotic Recommendations:
- If you are not allergic to penicillin, take 2grams of Amoxicillin by mouth one hour prior to your procedure
- You are allergic to penicillin, take 600mg of Clindamycin by mouth one hour prior to your procedure
Please try to avoid scheduling any elective dental procedure for at 3 months following your joint replacement
QUESTION: When my knee was replaced with an artificial joint, the surgeon said I should always take antibiotics before any dental procedure. He said the bacteria in my mouth could get into my bloodstream and cause an infection around the implant. But my dentist said not to worry and that I actually don’t need antibiotics. Who is correct?
ANSWER: For several years, orthopaedic surgeons and dentists have given conflicting advice about whether a patient with a prosthetic joint implant needs antibiotics to prevent potential infections – a practice known as antibiotic prophylaxis.
The surgeons believed that antibiotics were necessary because a joint infection could jeopardize the implant. Dentists, on the other hand, felt that mouth bacteria didn’t pose a risk to the implants and patients shouldn’t be taking the drugs needlessly.
The mixed messages have certainly caused confusion for a lot of patients. But, thankfully, the dentists and surgeons have finally settled their differences and come to a common position. After reviewing the available scientific evidence, they recently concluded that antibiotics aren’t needed before dental procedures after all.
The national bodies that represent the two professions (the Canadian Orthopaedic Association and the Canadian Dental Association), plus infectious disease specialists (the Association of Medical Microbiology and Infectious Disease Canada) have issued a joint statement calling for an end to the practice.
However, old habits die hard, acknowledges Dr. Tracy Wilson, an orthopaedic surgeon at the Thunder Bay Regional Health Sciences Centre and a member of the team that wrote the consensus statement.
“This is a pretty significant change for the orthopaedic group,” says Dr. Wilson. “It is going to take a while for us to know whether or not clinicians are actually changing their practice.”
To understand how we got to this point, it’s worthwhile reviewing the long history of this controversy.
Back in 2003, Canadian surgeons and dentists were on the same page. They both followed the example set by their U.S. counterparts (the American Academy of Orthopaedic Surgeons and the American Dental Association) who recommended that patients should take a dose of antibiotics one hour before dental procedures for the first two years after they received a knee or hip replacement.
It was hoped that antibiotics would reduce the theoretical risk of germs in the mouth getting into the bloodstream and travelling to the implant and possibly causing an infection.
But “there has never been any evidence” that mouth bacteria were the culprits in these infections, says Dr. Andrew Morris, an infectious disease physician at Mount Sinai Hospital, and also a member of the consensus statement team. Nor was there any proof that antibiotic prophylaxis was an effective infection prevention strategy, he adds.
Even so, the use of antibiotics seemed justified because the infections – which affect about 1 percent of knee and hip implant patients – can lead to extremely serious complications. Some patients must have their implants replaced, involving multiple surgeries, says Dr. Wilson.
Then in 2009, U.S. orthopaedic surgeons called for even stricter infection control measures, saying that joint-implant recipients should use antibiotics before every dental procedure – including routine cleaning – for the rest of their lives.
Meanwhile, Canadian dentists had begun to question antibiotic prophylaxis. They felt that the practice might be doing more harm than good, says Dr. Susan Sutherland, chief of dentistry at Sunnybrook Health Sciences Centre, and another consensus statement team member.
Antibiotics, she notes, can wipe out the so-called “good” gut bacteria that help to keep in check “bad” bacteria such as C. difficile, which can cause severe diarrhea. In some patients, C. difficile can be deadly.
Infectious disease experts also strongly opposed needless antibiotic prophylaxis. They expressed alarm that the overuse and misuse of antibiotics is fuelling the emergence of bacterial strains that are resistant to the life-saving medications – a threat to public health around the globe.
Furthermore, new researchseemed to exonerate mouth bacteria. Studies revealed that the type of bacteria found in most prosthetic joint infections normally live on the surface of skin – not in the mouth.
Dr. Morris speculates that the skin bacteria might enter the body through a cut or may simply get into the joint at the time of the operation – slowly multiplying until an infection becomes apparent. Some joint infections can arise months or years after the original surgery.
To further complicate matters, Canadian dentists and surgeons couldn’t agree on who should be responsible for writing the antibiotic prescriptions. Orthopaedic surgeons usually see patients for only a few follow-up visits after the operation. That meant the onus fell on the dentists because they have an ongoing relationship with the patients. But the dentists didn’t want to be prescribing an antibiotic which they increasingly felt was unnecessary, says Dr. Sutherland.
In order to resolve these differences, experts from the various sides began holding meetings to review the evidence. It was through this process – lasting more than two years – that they agreed antibiotic prophylaxis is generally unnecessary for patients with total joint replacements (knees and hips) and those with orthopaedic pins, plates and screws.
The consensus statement was approved this past summer, but it is taking time to get the message out to the medical community. So, some patients may continue to hear conflicting advice from their health-care professionals for a while yet.
It’s worth noting that there are still some patients who may require antibiotics before a dental visit, says Dr. Sutherland. “If a cancer patient is on chemotherapy and has a compromised immune system and can’t fight an infection, then antibiotics might be indicated.” But, she explains, these patients would be prescribed antibiotics even if they didn’t have joint implants. They are simply vulnerable to infection and need the added protection.
For the vast majority of patients with joint implants, antibiotics aren’t required prior to dental procedures. “That’s the bottom line,” says Dr. Sutherland.